sex hikayeleri interior desing escort fethiye escort denizli porno hikaye kredi kartı borç sorgulama sitesi yayında ziraatbank borç sorgulama
HEALTH / FITNESS NEWS
July 03, 2012 12:00:00 AM
  Follow @ Twitter

A lab test to screen embryos for inherited risk of breast or ovarian cancer is "feasible" but controversy surrounding this method is unlikely to be stilled, a fertility conference heard on Monday.

European researchers carried out the biggest-ever probe of a procedure to vet in-vitro embryos for gene mutations linked to these notorious cancers.

Their work, presented at a conference in Istanbul, declared the test is a reliable indicator of whether the embryo carries the dangerous BRCA1 and BRCA2 gene variants.

Even so, these genes are by no means a guarantee that cancer will occur, which means a fierce debate over the technique will continue, they said.

The method, called preimplantation genetic diagnosis (PGD), entails taking cells from an IVF embryo while it is still in its earliest stage.

If the embryo does not carry the flawed genes, it is deemed ready for transfer to the uterus, the next step of in-vitro fertilisation (IVF).

PGD has risen to prominence through screening for single-gene diseases such as cystic fibrosis that can doom a child to a life of sickness.

Its use is now being widened to cover the inherited risk for cancer, but this is still at a fledgling stage as doctors debate the pros and cons.

Presented at the annual conference of the European Society of Human Reproduction and Embryology (ESHRE), the new research looked at 717 IVF embryos that were screened for the BRCA1 and BRCA2 variants.

Seventy couples who took part in the study had sought PGD because one partner -- usually the woman -- had a family history of breast or ovarian cancer and they were afraid of handing on the risk to their child.

Of the 717 embryos, 43.1 percent carried a mutation while 40.7 percent were unaffected. The others either had gene abnormalities or analysis of them was inconclusive.

"Our results suggest that PGD for BRCA1 and BRCA2 mutations is feasible, with a good treatment outcome," Willem Verpoest, a professor at the Centre for Reproductive Medicine at Brussels' Free University, said in a press release.

"But controversy will still remain over the ethical acceptability of PGD for a susceptible, yet preventable, condition."

Cancer is a disease with genetic and environmental triggers. Female carriers of either BRCA1 or 2 mutations have a lifetime risk of 60-80 percent of breast cancer.

Carrying just the BRCA1 mutation carries a 30-60 percent risk of ovarian cancer in the course of a lifetime, which falls to five to 20 percent with BRCA2.

Yet many of these cancers occur late in life and there are constantly improving options for preventing and treating them.

This means that someone with the unlucky genes has a very high chance of many years of healthy life -- and a good chance of not developing cancer anyway. In addition, many other genes play a greater or lesser role in cancer.

PGD has also stirred ethical questions beyond the medical field, with critics fearing it could be used as a tool for creating designer babies.

AFP


PREVIOUS STORY
GlaxoSmithKline fined $3bn in US
NEXT STORY
US approves over-the-counter HIV home testing kit

Bookmark and Share
   




FIJI NEWS
Community service for ministry staffStaff of Fiji’s Ministry of Infrastructure and Transport in all departments throughout the divisions today carried out community works in seven (7) non-charitable organizations around the country.
SPORTS
Waqa double puts Ba in Champs League semisStriker Saula Waqa scored a goal in each half to guide Ba to 2-0 win over AS Pirae and push the Men In Black into the semi-finals of the 2015 Fiji Airways OFC Champions League.
TECHNOLOGY
$5000 boost to assist diabetes awareness programVodafone Fiji ATH Foundation has stepped in with financial boost to assist the Lions Club in their Diabetes Awareness program.
LIFESTYLE/FASHION
Fiji Link receives ATR72-600 aircraftFiji Airways, Fiji’s national airline, today received its latest ATR72-600 aircraft for its domestic subsidiary Fiji Link.
ENTERTAINMENT
The Rolling Stones’ Sticky Fingers to get deluxe reissueSticky Fingers, the 1971 classic which is one of the most revered albums in the catalogue of the legendary Rolling Stones, and which captured the band at their peak, on timeless tracks such as Brown Sugar, Wild Horses, Bitch, Sister Morphine and Dead Flowers, is to be reissued worldwide on May 22.
OFFBEAT
Mercury 'took Princess Diana to gay barQueen singer Freddie Mercury disguised the late Princess Diana as a male model and smuggled her into a notorious gay bar, according to a memoir serialised in Britain's Sunday Times.
NEWS SPORTS INFOTAINMENT SERVICES MOBILE EXTRA HOT TOPICS